Glycine → HCID 893637, compound

HRID 1249533Notes

Reaction equation

HRID 1249533 reaction equation
[NH2:1][CH2:2][C:3]([OH:5])=[O:4].[C:6]1([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:11]=[CH:10][C:9]([S:12](Cl)(=[O:14])=[O:13])=[CH:8][CH:7]=1.[OH-].[Na+].CCOCC>C1COCC1>[C:6]1([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:11]=[CH:10][C:9]([S:12]([NH:1][CH2:2][C:3]([OH:5])=[O:4])(=[O:14])=[O:13])=[CH:8][CH:7]=1

Participants

6

Reactant 4

HCID 750GlycineHCID 3283Diethyl EtherHCID 14798Sodium HydroxideHCID 74192(1,1'-Biphenyl)-4-sulphonyl chloride

Product 1

HCID 893637HCID 893637, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Glycine (5 mmol) is reacted with 4-biphenylsulfonyl chloride (about 5 mmol) in the presence of 1N NaOH solution (10 ml), ether (21 ml) and THF (2 ml) using the procedure described in Example 5 to give the title product.

Sources & evidence

ORD record
ord-615156024e484d57b5366ded4c73b59c
Source dataset
uspto-grants-1986_12
Patent number
US04632931

Reaction notes

Loading…