Phenoxyacetic Acid → Phenoxyacetyl chloride

HRID 1249655Notes

Reaction equation

HRID 1249655 reaction equation
[O:1]([CH2:8][C:9]([OH:11])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:14])=O>>[O:1]([CH2:8][C:9]([Cl:14])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 19188Phenoxyacetic AcidHCID 24386Thionyl Chloride

Product 1

HCID 69703Phenoxyacetyl chloride

Procedure

Phenoxyacetic acid (d5) was treated with 25 ml of thionyl chloride and stirred for 18 hours at room temperature. After the end of the reaction, the reaction mixture was concentrated under vacuum at 30° C. to provide phenoxyacetyl chloride (4.8 g).

Workup

  1. customAfter the end of the reaction
  2. concentrationthe reaction mixture was concentrated under vacuum at 30° C.

Sources & evidence

ORD record
ord-92b52fe2c1d64758b0993ba7f1a2bf6e
Source dataset
uspto-grants-2002_01
Patent number
US06334997B1

Reaction notes

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