Chlorosulfonic acid → HCID 18328737, compound

HRID 1249684Notes

Reaction equation

HRID 1249684 reaction equation
[C:1]1([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][C:4]([N:7]2[CH2:11][CH2:10][CH2:9][CH2:8]2)=[CH:3][CH:2]=1.[Cl:18][S:19](O)(=[O:21])=[O:20].C(=O)(O)[O-].[Na+]>>[N:7]1([C:4]2[CH:5]=[CH:6][C:1]([C:12]3[CH:13]=[CH:14][C:15]([S:19]([Cl:18])(=[O:21])=[O:20])=[CH:16][CH:17]=3)=[CH:2][CH:3]=2)[CH2:11][CH2:10][CH2:9][CH2:8]1

Participants

4

Reactant 3

HCID 24638Chlorosulfonic acidHCID 516892Sodium BicarbonateHCID 18328732HCID 18328732, compound

Product 1

HCID 18328737HCID 18328737, compound

Conditions

Temperature
60 °C

Procedure

6 g (0.023 mol) of the product from stage 1 was introduced into 11 ml of chlorosulfonic acid in portions with cooling and under protecting gas and the mixture was heated at 60° C. for 3.5 h. The solution was added to ice, the suspension was brought to pH 8 by addition of solid sodium bicarbonate, and the precipitated product was filtered off with suction and dried under reduced pressure.

Workup

  1. temperaturewith cooling
  2. additionThe solution was added to ice
  3. filtrationthe precipitated product was filtered off with suction
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-7a2cd48f846441dbb88228f6d6519a42
Source dataset
uspto-grants-2002_01
Patent number
US06335333B1

Reaction notes

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