反应详情

1.3 g (4 mmol) 1-ethyl-2-methoxymethyl-3-benzyloxy-6-methyl-pyridin-4(1H)-one hydrochloride was added to 40 ml of 4N hydrochloric acid and refluxed for 6 hours. Concentration to dryness in vacuo afforded the crude product. Recrystallisation from methanol/diethyl ether gave the pure title compound (0.7 g, 80%) as a yellow crystalline solid. m.p. 160-162° C.

1. temperaturerefluxed for 6 hours
2. concentrationConcentration to dryness in vacuo
3. customafforded the crude product
4. customRecrystallisation from methanol/diethyl ether