反应详情

2.0 g (7.33 mmol) 1-ethyl-2-methoxymethyl-3-benzyloxy-pyridin-4(1H)one was dissolved in 50 ml of 4N hydrochloric acid and refluxed for 6 hours. Concentration to dryness in vacuo afforded the crude product. Recrystallisation from methanol/diethyl ether gave the pure title compound (1.1 g, 73%) as a white crystalline solid. m.p. 168-169° C.

1. temperaturerefluxed for 6 hours
2. concentrationConcentration to dryness in vacuo
3. customafforded the crude product
4. customRecrystallisation from methanol/diethyl ether