反应详情

1-Hydroxy-2-(adamant-1-yl)ethane (901.0 mg, 5.0 mmol) was treated with phosphorus pentabromide(3.0 gm, 7.0 mmol) in diethyl ether and warmed slightly until a noticeable exotherm was observed. The resulting red solution was washed with aqueous sodium bicarbonate solution and dried (Na2SO4). Solvent removal gave crude 1-Bromo-2-(adamant-1-yl)ethane. The material was used as is without further purification.

1. temperaturewarmed slightly until a noticeable exotherm
2. washThe resulting red solution was washed with aqueous sodium bicarbonate solution
3. dry with materialdried (Na2SO4)
4. customSolvent removal