Acetic Acid → HCID 57043464, compound

HRID 1249974Notes

Reaction equation

HRID 1249974 reaction equation
O[C:2]1([C:8]2[CH:13]=[CH:12][C:11]([C:14]3[O:15]CC(C)(C)N=3)=[C:10]([CH3:21])[CH:9]=2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.Cl.C(O)(=[O:25])C>>[C:2]1([C:8]2[CH:13]=[CH:12][C:11]([C:14]([OH:15])=[O:25])=[C:10]([CH3:21])[CH:9]=2)[CH2:3][CH2:4][CH2:5][CH2:6][CH:7]=1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 18001102HCID 18001102, compound

Product 1

HCID 57043464HCID 57043464, compound

Procedure

To a solution of 2-[4-(1-hydroxy-1-cyclohexyl)-2-methylphenyl]-4,4-dimethyl-2-oxazoline (4.29 g) in acetic acid (40 ml) is added a 10% hydrochloric acid (20 ml), and the mixture is refluxed for two days. The precipitated crystals are collected by filtration, washed with water, and dried to give 4-cyclohexenyl-2-methylbenzoic acid (2.61 g) as white powder.

Workup

  1. temperaturethe mixture is refluxed for two days
  2. filtrationThe precipitated crystals are collected by filtration
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-6d3eb72f1f01481ab741d54dd1bbcfd6
Source dataset
uspto-grants-2002_01
Patent number
US06335327B1

Reaction notes

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