Potassium Carbonate → HCID 18327278, compound

Participants

Reaction Steps

At 23° C., 2.0 g of 3-chloro-2-(2,3-dichloro-4-hydroxybenzyl)-5-trifluoromethylpyridine, 1.5 g of anhydrous potassium carbonate and 1.0 g of methyl bromoacetate were stirred in 60 ml of anhydrous dimethylformamide for 16 hours. The reaction mixture was then poured into 400 ml of ice-water. The resulting solid product was separated off, washed with water and purified by stirring in n-hexane. Yield: 2.4 g (100%; white crystals); mp.: 110-111° C.

Provenance & Evidence