HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-indole → 4-(6-Fluoro-1H-indol-3-YL)cyclohexanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-indole | HCID 10848753 | — |
| Reactant | 3-(1,4-Dioxa-spiro[4,5]dec-8-yl)-6-fluoro-1H-indole | HCID 18414086 | — |
| Product | 4-(6-Fluoro-1H-indol-3-YL)cyclohexanone | HCID 15481281 | 60% |
Reaction Steps
The title compound was prepared according to the procedure of Example 1, Step 3 except that 3-(1,4-dioxa-spiro[4.5]dec-8-yl)-6-fluoro-1H-indole was used instead 3-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1H-indole. Yield: 60%; MS (ES) m/z (relative intensity): 429 (M++H, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06337326B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-e627997d3ded41178a95ab0b34d93b17 |
| Source note | uspto-grants-2002_01 |