HCID 70167036, compound → HCID 70165935, compound

Participants

Reaction Steps

A solution of 2-[2-(4-chloro-phenyl)-vinyl]-8-methoxy-3-[3-(1-phenethyl-piperidin-4-yl)-propyl]-3H-quinazolin-4-one (530 mg, 0.98 mmol) in conc HBr/HOAc (1:1 mixture, 60 mL) was heated at 120° C. for 48 h. After cooling to room temperature, the reaction mixture was concentrated under vacuum to yield the desired product. API-MS: 529 (M+1)

Provenance & Evidence