反应详情

A solution of compound 5 (5.25 g, 0.014 mol) and aqueous ammonia (35% w/v, 100 ml) in ethanol (200 ml) was stirred for 1 h at room temperature. TLC analysis (dichloromethane) revealed a complete reaction. The solvent was removed in vacuo and the white solid was recrystallised from ethanol to give colourless crystals.

1. customa complete reaction
2. customThe solvent was removed in vacuo
3. customthe white solid was recrystallised from ethanol
4. customto give colourless crystals