HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → Octyl 4'-hydroxy-4-biphenylcarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Octyl4'-methoxycarbonyloxy-4-biphenylcarboxylate | HCID 18328376 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Octyl 4'-hydroxy-4-biphenylcarboxylate | HCID 14692993 | — |
Reaction Steps
A solution of compound 5 (5.25 g, 0.014 mol) and aqueous ammonia (35% w/v, 100 ml) in ethanol (200 ml) was stirred for 1 h at room temperature. TLC analysis (dichloromethane) revealed a complete reaction. The solvent was removed in vacuo and the white solid was recrystallised from ethanol to give colourless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06337420B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-c4487588a82e4d27b7e1d34260227de1 |
| Source note | uspto-grants-2002_01 |