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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1250557Generated: November 1, 2026

Allylamine → 2,4-Diallylamino-6-nitroquinazoline

https://huagongshe.com/reaction/1250557

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAllylamineHCID 7853—
Reactant4-Allylamino-2-chloro-6-nitroquinazolineHCID 18326487—
SolventWaterHCID 962—
Product2,4-Diallylamino-6-nitroquinazolineHCID 5711744680.6%

Reaction Steps

A mixture of 265 mg (1.00 mmol) of 4-allylamino-2-chloro-6-nitroquinazoline and 1.52 g (26.65 mmol) of allylamine were stirred at room temperature for 2.5 hours. Water was added to the reaction mixture, and crystals thus precipitated were filtered out to give 230 mg (yield: 80.6%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06339089B2
Source datasetuspto-grants-2002_01
ORD IDord-d1ab6a985b6c42d8843a992088c45bf1
Source noteuspto-grants-2002_01