HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargylamine → HCID 18326417, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargylamine | HCID 239041 | — |
| Reactant | 4-Allylamino-2-chloro-6-nitroquinazoline | HCID 18326487 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 18326417 | HCID 18326417 | 88.6% |
Reaction Steps
To 150 mg (0.57 mmol) of 4-allylamino-2-chloro-6-nitroquinazoline was added 1.61 g (29.16 mmol) of 2-propynylamine, followed by stirring at room temperature for 6 hours. After water was added to the reaction solution was water added, crystals thus precipitated were filtered and recrystallized from ethyl acetate-hexane to give 143 mg (yield: 88.6%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06339089B2 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-26072ec2c1014aea9467fc63d3e95207 |
| Source note | uspto-grants-2002_01 |