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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1250584Generated: November 3, 2026

Propargylamine → HCID 18326417, compound

https://huagongshe.com/reaction/1250584

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropargylamineHCID 239041—
Reactant4-Allylamino-2-chloro-6-nitroquinazolineHCID 18326487—
SolventWaterHCID 962—
ProductHCID 18326417HCID 1832641788.6%

Reaction Steps

To 150 mg (0.57 mmol) of 4-allylamino-2-chloro-6-nitroquinazoline was added 1.61 g (29.16 mmol) of 2-propynylamine, followed by stirring at room temperature for 6 hours. After water was added to the reaction solution was water added, crystals thus precipitated were filtered and recrystallized from ethyl acetate-hexane to give 143 mg (yield: 88.6%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06339089B2
Source datasetuspto-grants-2002_01
ORD IDord-26072ec2c1014aea9467fc63d3e95207
Source noteuspto-grants-2002_01