HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18326431, compound → HCID 18326505, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18326431 | HCID 18326431 | — |
| Reactant | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 18326505 | HCID 18326505 | 90.3% |
Reaction Steps
A 4 N hydrochloric acid-ethyl acetate solution was added dropwise to a solution of 398 mg (1.3 mmol) of 2-allylamino-4-(t-butylcarbamoyl)amino-7-methylthieno[3,2-d]pyrimidine in ethyl acetate under ice cooling. Crystals thus precipitated were filtered out to give 400 mg (yield: 90.3%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06339089B2 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-ca4bbc875ac84b2faaad244f45da4171 |
| Source note | uspto-grants-2002_01 |