Dichloromethane → 2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-amine

HRID 125076Notes

Reaction equation

HRID 125076 reaction equation
[Cl:1][c:2]1[n:3][c:4]([N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([NH:11][C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[s:10]2.[Cl:25][CH2:26][Cl:27].[F:28][C:29]([F:30])([F:31])[C:32]([OH:33])=[O:34]>>[Cl:1][c:2]1[n:3][c:4]([N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([NH2:11])[s:10]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 59592872Tert-butyl 2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-ylcarbamate

Product 1

HCID 595928682-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-amine

Sources & evidence

ORD record
ord-c6cb32d14db041dcaa4ede81d857410a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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