HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1250778Generated: October 25, 2026
1-Methylpiperazine → 2-(2-Hydroxyphenyl)-1-(4-methylpiperazino)-1-ethanone
https://huagongshe.com/reaction/1250778
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 2(3H)-Benzofuranone | HCID 68382 | — |
| Product | 2-(2-Hydroxyphenyl)-1-(4-methylpiperazino)-1-ethanone | HCID 18520258 | 101.7% |
Reaction Steps
N-Methylpiperazine (1.52 g) was added to 2-coumaranone (2.01 g) and stirred for 3.5 hours at 85° C., thereby yielding the entitled compound (3.57 g) as pale brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06339154B1 |
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| Source dataset | uspto-grants-2002_01 |
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| ORD ID | ord-7ba78af36f1645d381e9675a77a3bd69 |
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| Source note | uspto-grants-2002_01 |
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