反应详情

To a solution of 0.69 g of 4-(4-hydroxyphenyl)butyric acid in 10 mL of DMF was added 0.956 g of sodium bicarbonate followed by 0.36 mL of iodomethane and the resulting mixture was stirred at room temperature for 5 h. The reaction was then diluted with water, extracted with ether, dried over MgSO4, filtered and concentrated in vacuo to provide 0.553 g of methyl 4(4-hydroxyphenyl)butyrate.

1. extractionextracted with ether
2. dry with materialdried over MgSO4
3. filtrationfiltered
4. concentrationconcentrated in vacuo