HCID 18325115, compound → HCID 18325136, compound

Participants

Reaction Steps

To a solution of a crude crystal (1.0 g) of 2-[4-(4-fluorophenyl)-2-hydroxymethyl-6-methoxyquinolin-3-yl]-1-ethanol in chloroform (100 ml), manganese dioxide (10 g) was added, followed by stirring at room temperature for 2 hours. After the manganese dioxide was filtered off, the reaction mixture was concentrated under reduced pressure; the residue obtained was recrystallized from THF to yield the title compound (335 mg).

Provenance & Evidence