Methylamine → HCID 9864602, compound

HRID 1250949Notes

Reaction equation

[CH:1]1[C:6]2[CH:7]=[C:8]3[C:22](=[O:23])[O:21][CH2:20][C:9]3=[C:10]([C:11]3[CH:12]=[CH:13][C:14]4[O:19][CH2:18][O:17][C:15]=4[CH:16]=3)[C:5]=2[C:4]2[O:24][CH2:25][O:26][C:3]=2[CH:2]=1.[CH3:27][NH2:28]>C1C=CC=CC=1>[CH3:27][NH:28][C:22]([C:8]1[CH:7]=[C:6]2[C:5](=[C:10]([C:11]3[CH:12]=[CH:13][C:14]4[O:19][CH2:18][O:17][C:15]=4[CH:16]=3)[C:9]=1[CH2:20][OH:21])[C:4]1[O:24][CH2:25][O:26][C:3]=1[CH:2]=[CH:1]2)=[O:23]

Participants

Conditions

Temperature: 120 °C

Procedure

Helioxanthin (1.0 g) was suspended in benzene (10 ml), followed by addition of methylamine (40% methanol solution: 2 ml). The mixture was heated at 120° C. under stirring for 4 days. The reaction mixture was concentrated under reduced pressure. The resulting residue was recrystalized from DMF to yield the title compound (144 mg).

Workup

concentrationThe reaction mixture was concentrated under reduced pressure
customThe resulting residue was recrystalized from DMF

Sources & evidence

ORD record: ord-ca3e1b4690e341a4af366c7823cacc25
Source dataset: uspto-grants-2002_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06340704B1

Reaction notes

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