反应详情

2-Methyl-3-thiophenecarboxylic acid (54 g) was reacted with thionyl chloride (100 ml) at 60° C. for 1.5 hr. The reaction solution was evaporated, and to the resulting residue was added THF (100 ml×2), and then excess thionyl chloride was removed, to give 60.5 g of the title compound.

1. customThe reaction solution was evaporated
2. additionto the resulting residue was added THF (100 ml×2)
3. customexcess thionyl chloride was removed