HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone Cyanohydrin → HCID 18323946, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone Cyanohydrin | HCID 6406 | — |
| Reactant | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| Reactant | Dimethylacetamide | HCID 31374 | — |
| Reactant | Tetrahydrothiopyran-4-one | HCID 66173 | — |
| Reactant | Piperidin-4-ol | HCID 79341 | — |
| Product | HCID 18323946 | HCID 18323946 | — |
Reaction Steps
It is prepared from MgSO4 (7.2 g, 60 mmoles), DMA (2.62 g, 30 mmoles), 4-hydroxy-piperidine (3.03 g, 20 mmoles), tetrahydro-4H-thiopyran-4-one (2.32 g, 20 mmoles) and acetone cyanhydrin (1.7 g, 20 mmoles). After treatment of the reaction, a white solid is obtained (4.7 g) which is crystallized from anhydrous ether. In this way, white crystals are obtained (3.6 g, 79%). M.p.=79-81° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06342511B1 |
| Source dataset | uspto-grants-2002_01 |
| ORD ID | ord-eacb37ce01b34d108084f991eea0e370 |
| Source note | uspto-grants-2002_01 |