Acetic Anhydride → 1,3,5-Triazine, 2,4-dimethoxy-6-methyl-

HRID 1251535Notes

Reaction equation

HRID 1251535 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[C:7]([CH3:9])[N:6]=[C:5](NC)[N:4]=1.[C:12](OC(=O)C)(=[O:14])C>[Zn]>[CH3:12][O:14][C:5]1[N:4]=[C:3]([O:2][CH3:1])[N:8]=[C:7]([CH3:9])[N:6]=1

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 1607791,3,5-Triazin-2-amine, 4-methoxy-N,6-dimethyl-

Product 1

HCID 199041,3,5-Triazine, 2,4-dimethoxy-6-methyl-

Reagents, catalysts & solvents 1

HCID 23994ZincCatalyst

Procedure

Provided herein is a novel and useful process for preparing 2-methoxy-4-methyl-6-methylamino-1,3,5-triazine that broadly comprises the steps of (a) reacting zinc bis(imino-bis-carbimic acid methyl ester) with acetic anhydride to give 2,4-dimethoxy-6-methyl-1,3,5-triazine and (b) reacting the 2,4-dimethoxy-6-methyl-1,3,5-triazine, formed in step (a), with methylamine to give 2-methoxy-4-methyl-6-methylamino-1,3,5-triazine.

Workup

  1. customProvided herein

Sources & evidence

ORD record
ord-5c425e43e976467d81309fbf85bff1dd
Source dataset
uspto-grants-2002_01
Patent number
US06342600B1

Reaction notes

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