Propionic Acid → HCID 11121055, compound

HRID 1251556Notes

Reaction equation

HRID 1251556 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2([CH2:17][CH2:18][C:19](N3CCCCC3)=[O:20])[CH2:14][CH2:13][C:12](=[O:15])[NH:11][C:10]2=[O:16])[CH:5]=[CH:6][C:7]=1[Cl:8].C(O)(=[O:30])CC>Cl>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2([CH2:17][CH2:18][C:19]([OH:20])=[O:30])[CH2:14][CH2:13][C:12](=[O:15])[NH:11][C:10]2=[O:16])[CH:5]=[CH:6][C:7]=1[Cl:8]

Participants

4

Reactant 2

HCID 1032Propionic AcidHCID 15516359HCID 15516359, compound

Product 1

HCID 11121055HCID 11121055, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

The compound obtained in EXAMPLE 2 is taken up in 0.5 ml of propionic acid and placed in a tube sealed under vacuum. After 18 hours at 145° C., the reaction mixture and diluted with 10 ml of 1 N HCl. After one day, the product which crystallizes is filtered, drained and dried. 100 mg of the expected compound are obtained.

Workup

  1. customplaced in a tube
  2. customsealed under vacuum
  3. waitAfter one day
  4. customthe product which crystallizes
  5. filtrationis filtered
  6. customdried

Sources & evidence

ORD record
ord-5195178b2d4d4197b1c7f02d870cefc3
Source dataset
uspto-grants-2002_01
Patent number
US06342607B1

Reaction notes

Loading…