HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dimethylformamide → 2-Ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dimethylformamide | HCID 6228 | — |
| Edukt | Sulfuryl chloride | HCID 24648 | — |
| Edukt | 2-Ethyl-5-methylbenzo[b]thiophene | HCID 595344 | — |
| Produkt | 2-Ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride | HCID 22998437 | — |
Reaktionsschritte
2-ethyl-5-methylbenzo[b]thiophene-3-sulfonylchloride was prepared in the same manner as described in Example 40B. Reaction of DMF (6.5 mmoles, 0.50 ml), sulfurylchloride (5.5 mmoles, 0.44 ml) and 2-ethyl-5-methylbenzo[b]thiophene (3.2 mmoles, 0.57 g) yielded, after flash chromatography, using 2% ethyl acetate/hexanes, 0.58 g (66%) of an orange solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06342610B2 |
| Quelldatensatz | uspto-grants-2002_01 |
| ORD ID | ord-d9f3b05173a5494aac37490f028e3aaf |
| Quellennotiz | uspto-grants-2002_01 |