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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1251898Generated: November 2, 2026

Sodium Hydroxide → 5-[1-(Thiazol-2-yl)-2-(imidazol-1-yl)ethoxy]-2-(4-fluorophenethyl)benzoic acid

https://huagongshe.com/reaction/1251898

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantMethyl 5-[2-(imidazol-1-yl)-1-(thiazol-2-yl)ethoxy]-2-(4-fluorophenethyl)benzoateHCID 18324507—
Product5-[1-(Thiazol-2-yl)-2-(imidazol-1-yl)ethoxy]-2-(4-fluorophenethyl)benzoic acidHCID 18324428—

Reaction Steps

Methyl 5-[2-(imidazol-1-yl)-1-(thiazol-2-yl)ethoxy]-2-(4-fluorophenethyl)benzoate was hydrolysed using aqueous sodium hydroxide solution to give 5-[2-(imidazol-1-yl)-1-(thiazol-2-yl)ethoxy]-2-(4-fluorophenethyl)benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06342765B1
Source datasetuspto-grants-2002_01
ORD IDord-9433cc22802745aca9e7b1a17d4b6231
Source noteuspto-grants-2002_01