反应详情

Methyl 5-[1-(4-fluorophenyl)-2-(2-methylimidazol-1-yl)ethoxy]-2-(4-fluorophenethyl)benzoate (4.2 g, ˜8.8 mmol) was hydrolysed with aqueous sodium hydroxide solution under the usual conditions to give 5-[1-(4-fluorophenyl)-2-(2-methylimidazol-1-yl)ethoxy]-2-(4-fluorophenethyl)benzoic acid (1.84 g, ˜45% ) as a colourless gum.