HCID 86585139, compound → HCID 9893825, compound

Participants

Reaction Steps

A solution of tert-butyl (2S)-2-{2-(4-fluorophenyl)-6-[1-(4-fluorophenyl)-2-(imidazol-1-yl)ethoxy]pyrid-3-oylamino}-4-methylsulfanylbutyrate (0.1 g.) in TFA(20 ml.) was stirred at ambient temperature under an inert atmosphere for 30 minutes. The TFA was evaporated away and the residue was converted to the hydrochloride salt to give (2S)-2-{2-(4-fluorophenyl)-6-[1-(4-fluorophenyl)-2-(imidazol-1-yl)ethoxy]pyrid-3-oylamino}-4-methylsulfanylbutyric acid as a white solid (0.092 g.).

Provenance & Evidence