HCID 53889356, compound → HCID 17866964, compound

Participants

Reaction Steps

A suspension of 10% palladium on carbon (2.5 g) and methyl 3-[2-(4-fluorophenyl)ethenyl]pyridin-2-carboxylate (12.4 g) in ethyl acetate (200 ml) was stirred vigorously under an hydrogen atmosphere at ambient temperature for four hours. The suspension was filtered through Celite and the filtrate concentrated under reduced pressure to give methyl 3-(4-fluoropbenethyl)pyridin-2-carboxylate as a mobile, pale yellow oil (11.72 g).

Provenance & Evidence