Borane → HCID 14004010, compound

HRID 1252119Notes

Reaction equation

HRID 1252119 reaction equation
[Cl:1][C:2]1[C:3]([Cl:17])=[CH:4][C:5]2[C:14]3[NH:13][C:12](=O)[CH2:11][CH2:10][C:9]=3[N:8]=[CH:7][C:6]=2[CH:16]=1.B>O1CCCC1>[Cl:1][C:2]1[C:3]([Cl:17])=[CH:4][C:5]2[C:14]3[NH:13][CH2:12][CH2:11][CH2:10][C:9]=3[N:8]=[CH:7][C:6]=2[CH:16]=1

Participants

4

Reactant 2

HCID 6331Borane2×HCID 14004004HCID 14004004, compound

Product 1

HCID 14004010HCID 14004010, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a stirred solution of 4.00 g of 8,9-dichloro-1,4-dihydrobenzo[c]-1,5-naphthyridin-2(3H)-one in tetrahydrofuran (800 ml) was added 60 ml of borane solution (1.0M in tetrahydrofuran) over approximately one minute. A solution formed after the borane addition was complete. The solution was stirred overnight at ambient temperature.

Workup

  1. customA solution formed

Sources & evidence

ORD record
ord-a30477c1c6cc4a53a0d44fb74a59d061
Source dataset
uspto-grants-1988_05
Patent number
US04742061

Reaction notes

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