HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-t-Butyloxycarbonylphenyl)acrylic acid ethyl ester → Tert-butyl 4-(3-ethoxy-3-oxopropyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-t-Butyloxycarbonylphenyl)acrylic acid ethyl ester | HCID 53791281 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Tert-butyl 4-(3-ethoxy-3-oxopropyl)benzoate | HCID 9993703 | — |
Reaction Steps
A mixture of 3-(4-t-butyloxycarbonylphenyl)acrylic acid ethyl ester (11.52 g) and 5% palladium-charcoal in ethanol (115 ml) was stirred under hydrogen atmosphere at room temperature. The catalyst was removed by filtration and washed with ethanol. The combined solution was evaporated to give 3-(4-tert-butyloxycarbonylphenyl)propionic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04742052 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-f068d433740847b5ac8ad7a6e65cb2dc |
| Source note | uspto-grants-1988_05 |