m-Chloroperbenzoic acid → HCID 20140933, compound

HRID 1252276Notes

Reaction equation

HRID 1252276 reaction equation
[CH3:1][C:2]([C:6]1[O:11][C:10](=[O:12])[N:9]([CH:13]([CH3:15])[CH3:14])[CH2:8][N:7]=1)([S:4][CH3:5])[CH3:3].ClC1C=CC=C(C(OO)=[O:24])C=1>C(Cl)(Cl)Cl>[CH3:3][C:2]([C:6]1[O:11][C:10](=[O:12])[N:9]([CH:13]([CH3:15])[CH3:14])[CH2:8][N:7]=1)([S:4]([CH3:5])=[O:24])[CH3:1]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 20140932HCID 20140932, compound

Product 1

HCID 20140933HCID 20140933, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

11.5 g of 6-(1-methyl-1-methylmercaptoethyl)-3-isopropyl-3,4-dihydro-2H-1,3,5-oxadiazin-2-one (Example 1) are dissolved in 100 ml of chloroform. The resultant solution is cooled to -10° C., and a solution of 9.5 g of m-chloroperbenzoic acid in 120 ml of chloroform is then added dropwise. The reaction mixture is subsequently stirred for 1 hour at room temperature and then concentrated. The residual crude product is recrystallised from a 1:1 mixture of ethyl acetate and hexane, affording the title compound of the formula ##STR7## with a melting point of 120-°121° C. (compound 2).

Workup

  1. concentrationconcentrated
  2. customThe residual crude product is recrystallised from a 1:1 mixture of ethyl acetate and hexane

Sources & evidence

ORD record
ord-c67a444857df4e5ca45f80a3f7b44b9e
Source dataset
uspto-grants-1988_05
Patent number
US04742056

Reaction notes

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