HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopropanoyl chloride → N-(2,3-dihydro-2,2-dimethylbenzofuran-5-yl)sulfonyl-2-bromopropionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopropanoyl chloride | HCID 97980 | — |
| Reactant | 2,2-Dimethyl-2,3-dihydro-1-benzofuran-5-sulfonamide | HCID 15611039 | — |
| Product | N-(2,3-dihydro-2,2-dimethylbenzofuran-5-yl)sulfonyl-2-bromopropionamide | HCID 15611041 | 87.7% |
Reaction Steps
In a manner similar to Step C of Example 9, the reaction of 4.0 g (0.017 mole) of 5-aminosulfonyl-2,3-dihydro-2,2-dimethylbenzofuran with 7.0 mL (0.069 mole) of 2-bromopropionyl chloride produced 5.4 g of N-(2,3-dihydro-2,2-dimethylbenzofuran-5-yl)sulfonyl-2-bromopropionamide as a solid (mp 125°-128° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04743291 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-95b4aff0f0ce4611af661d5a22bc0365 |
| Source note | uspto-grants-1988_05 |