1,1,1-Trimethoxybutane → 5-Methyl-4-imidazolecarboxylic acid, 2-(1-methoxybutylidene)hydrazide

HRID 1252366Notes

Reaction equation

HRID 1252366 reaction equation
[CH3:1][C:2]1[NH:6][CH:5]=[N:4][C:3]=1[C:7]([NH:9][NH2:10])=[O:8].[CH3:11][O:12][C:13](OC)(OC)[CH2:14][CH2:15][CH3:16]>C(O)C>[CH3:11][O:12][C:13](=[N:10][NH:9][C:7]([C:3]1[N:4]=[CH:5][NH:6][C:2]=1[CH3:1])=[O:8])[CH2:14][CH2:15][CH3:16]

Participants

4

Reactant 2

HCID 1235121,1,1-TrimethoxybutaneHCID 129532705-Methyl-1H-imidazole-4-carbohydrazide

Product 1

HCID 573044605-Methyl-4-imidazolecarboxylic acid, 2-(1-methoxybutylidene)hydrazide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 10 g of 5-methyl-1H-imidazole-4-carboxylic acid hydrazide, 80 ml of trimethylorthobutyrate and 395 ml of absolute ethanol was treated and described in Example 1, giving 16.5 g of 5-methyl-4-imidazolecarboxylic acid, 2-(1-methoxybutylidene)hydrazide.

Workup

  1. additionwas treated

Sources & evidence

ORD record
ord-2d9aeb3eead34b789fd849770c530202
Source dataset
uspto-grants-1988_05
Patent number
US04743586

Reaction notes

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