Isatoic Anhydride → HCID 14255054, compound

HRID 1252487Notes

Reaction equation

HRID 1252487 reaction equation
[C:1]12[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=1)[NH:6]C(=O)[O:4][C:2]2=O.[N:13]1[CH:18]=[CH:17][CH:16]=[C:15]([CH2:19][CH2:20][NH2:21])[CH:14]=1>C(O)C>[NH2:6][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:1]=1[C:2]([NH:21][CH2:20][CH2:19][C:15]1[CH:14]=[N:13][CH:18]=[CH:17][CH:16]=1)=[O:4]

Participants

4

Reactant 2

HCID 8359Isatoic AnhydrideHCID 8540512-(Pyridin-3-yl)ethan-1-amine

Product 1

HCID 14255054HCID 14255054, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 4.89 g of isatoic anhydride, 3.66 g of 2-(3-pyridinyl)ethylamine and 40 ml of ethanol was stirred at room temperature for 22 hours. The reaction mixture was concentrated and the residue was dissolved in ethyl acetate and cooled. The desired product was isolated by filtration, mp 126°-128° C.

Workup

  1. concentrationThe reaction mixture was concentrated
  2. dissolutionthe residue was dissolved in ethyl acetate
  3. temperaturecooled

Sources & evidence

ORD record
ord-b8aee358253345de95442f3df219b01a
Source dataset
uspto-grants-1988_05
Patent number
US04743610

Reaction notes

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