Benzoylacetone → HCID 53686411, compound

HRID 1252517Notes

Reaction equation

HRID 1252517 reaction equation
[C:1]([CH2:9][C:10](=[O:12])[CH3:11])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:14]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])=[O:15].C(N(CC)CC)C>C(OCC)C>[CH2:17]([O:16][C:14]([O:12][C:10]([CH3:11])=[CH:9][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[O:15])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]

Participants

5

Reactant 3

HCID 7166BenzoylacetoneHCID 8471TriethylamineHCID 97633Cetyl chloroformate

Product 1

HCID 53686411HCID 53686411, compoundYield 80.6%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The preparation is carried out as described in Example 1, using 17.8 g (0.11 mole) of benzoylacetone, 30.5 g (0.1 mole) of n-hexadecyl chloroformate and 100 ml of diethyl ether as well as 11 g (0.11 mole) of triethylamine. The crude product (34.7 g) obtained is recrystallised from a mixture of 85 ml of isopropanol and 10 ml of water. The white crystals melt at 31° C.

Sources & evidence

ORD record
ord-27ca25af14464bc4b7d5f813a49505aa
Source dataset
uspto-grants-1988_05
Patent number
US04743640

Reaction notes

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