HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(5-Bromo-3-methyl-2-pyridinyl)butylamine → HCID 178422455, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(5-Bromo-3-methyl-2-pyridinyl)butylamine | HCID 13094272 | — |
| Reactant | 87476-69-5 | HCID 14154299 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 178422455 | HCID 178422455 | — |
Reaction Steps
A slurry of 4-(5-bromo-3-methyl-2-pyridinyl)butylamine (252 mg, 1.04 mmol) and 6-bromo-3-chlorobenzisothiazole 1,1-dioxide (U.S. Pat. No. 4,490,527) (292 mg, 1.04 mmol) in 15 ml acetonitrile was heated under dry nitrogen until nearly completely dissolved, when the above compound precipitated as the hydrochloride salt, yielding 360 mg (66%), m.p. 224°-232° C. IR(KBr) 1620, 1300, 1160, 650 cm-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04743692 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-777d15afcd304d3ea73ef0af1cbb43ad |
| Source note | uspto-grants-1988_05 |