Hydrochloric Acid → HCID 14579493, compound

HRID 1252561Notes

Reaction equation

HRID 1252561 reaction equation
[F:1][CH2:2][C:3]([N:19]=CC1C=CC=CC=1)([CH2:8][CH2:9][CH2:10][N:11]=CC1C=CC=CC=1)[C:4]([O:6][CH3:7])=[O:5].[ClH:27]>C(OCC)C>[ClH:27].[ClH:27].[F:1][CH2:2][C:3]([NH2:19])([CH2:8][CH2:9][CH2:10][NH2:11])[C:4]([O:6][CH3:7])=[O:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19851098HCID 19851098, compound

Product 1

HCID 14579493HCID 14579493, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A mixture of methyl 2-fluoromethyl-2,5-bis(benzylideneamino)pentanoate (3.11 g) in diethyl ether (20 ml) and N aqueous HCl (100 ml) is stirred at room temperature for 3 hours. The aqueous phase is decanted, washed with ether, and concentrated in vacuo to give 2.5 g of methyl 2-fluoromethyl-2,5-diaminopentanoate dihydrochloride.

Workup

  1. customThe aqueous phase is decanted
  2. washwashed with ether
  3. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-25c5b17dc8144b0f91e7defb01cad1be
Source dataset
uspto-grants-1988_05
Patent number
US04743691

Reaction notes

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