HCID 57237301, compound → HCID 86742170, compound

Participants

Reaction Steps

3-[1,4-Dihydro-4-oxo-5-(phenylmethoxy)-2-pyridinyl]-2-propenoic acid, 2-[(1,1-dimethylethoxy)carbonyl]hydrazide (3.86 g) was stirred for one-half hour in 30 ml of trifluoroacetic acid at 0°-5° C. The trifluoroacetic acid salt of the title compound precipitated after adding 50 ml of diethylether. The salt was suspended in 30 ml of water, stirred with 2 g of sodium bicarbonate for 20 minutes, and the title compound was filtered off, washed with water and dried yielding a beige powder. Yield: 2.75 g.

Provenance & Evidence