Methylamine → 2-Chloro-4-methylamino-6-amino-1,3,5-triazine-

HRID 1252644Notes

Reaction equation

HRID 1252644 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([Cl:8])[N:5]=[C:4](Cl)[N:3]=1.[CH3:10][NH2:11]>CC(C)=O>[NH2:11][C:10]1[N:5]=[C:6]([Cl:8])[N:7]=[C:2]([NH:3][CH3:4])[N:1]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 136154,6-Dichloro-1,3,5-trazin-2-amine

Product 1

HCID 2249702-Chloro-4-methylamino-6-amino-1,3,5-triazine-

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of 2-amino-4,6-dichloro-1,3,5-triazine (0.2 mole) in 200 ml reagent grade acetone was cooled to 0° C. Two equivalents of 40% aqueous methylamine were added dropwise keeping the temperature less than 10° C.; solids precipitated during the addition. The reaction was then warmed to room temperature and stirred overnight under N2.

Workup

  1. customthe temperature less than 10° C.
  2. customsolids precipitated during the addition

Sources & evidence

ORD record
ord-19740ad62a08422db606d9cf96b3d4e5
Source dataset
uspto-grants-1988_05
Patent number
US04744816

Reaction notes

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