HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-(2-Mercaptomethyl-3-mercaptopropanoyl)-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (2-Acetylthiomethyl-3-(acetylthio)propanoyl]-L-proline | HCID 13145535 | — |
| Solvent | Ammonia | HCID 222 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-(2-Mercaptomethyl-3-mercaptopropanoyl)-L-proline | HCID 13145537 | — |
Reaction Steps
N-[(2-Acetylthiomethyl-3-(acetylthio)propanoyl]-L-proline (1.2 g) is dissolved in a mixture of water (12 ml) and concentrated ammonia (12 ml) under an atmosphere of argon. After twenty minutes, the mixture is acidified with concentrated hydrochloric acid. The crystalline precipitate N-(2-mercaptomethyl-3-mercaptopropanoyl)-L-proline is filtered and dried, yielding 0.63 g, m.p. 138°-140°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04745124 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-49dede41a75240a5ac2251b2e333dbeb |
| Source note | uspto-grants-1988_05 |