反应详情

N-[(2-Acetylthiomethyl-3-(acetylthio)propanoyl]-L-proline (1.2 g) is dissolved in a mixture of water (12 ml) and concentrated ammonia (12 ml) under an atmosphere of argon. After twenty minutes, the mixture is acidified with concentrated hydrochloric acid. The crystalline precipitate N-(2-mercaptomethyl-3-mercaptopropanoyl)-L-proline is filtered and dried, yielding 0.63 g, m.p. 138°-140°.

1. waitAfter twenty minutes
2. filtrationThe crystalline precipitate N-(2-mercaptomethyl-3-mercaptopropanoyl)-L-proline is filtered
3. customdried
4. customyielding 0.63 g, m.p. 138°-140°