2-Methylpyrrolidine → HCID 20138007, compound

Participants

Reaction Steps

To a solution of 8-(2-chloroethyl)-6,7,8,9-tetrahydro-6-methyl-5H-pyrido[3,2-c]azepin-5-one in ethanol was added 2-methylpyrrolidine. The solution is heated to reflux for several hours and ethanol is removed by evaporation. The residue is partitioned between dilute aqueous base and chloroform and the chloroform layer concentrated and the title compound isolated by an appropriate technique, e.g., distillation.

Provenance & Evidence