反应详情

Into a 100-ml egg plant type flask were placed 2.4 g of 1-(p-chlorophenoxy)-3,3-dimethyl-4-hydroxy-2-butanone, 2.6 g of triphenylphosphine and 50 ml of carbon tetrachloride, which were then refluxed for 18 hours. The reaction mixture was cooled, the crystals separating out were filtered off, and the filtrate was concentrated in a vacuum. The residue obtained was purified by silica gel column chromatography, giving 1.8 g of the above-identified desired compound.

1. customInto a 100-ml egg plant type flask were placed
2. temperatureThe reaction mixture was cooled
3. customthe crystals separating out
4. filtrationwere filtered off
5. concentrationthe filtrate was concentrated in a vacuum
6. customThe residue obtained
7. customwas purified by silica gel column chromatography