Carbon Dioxide → HCID 14638217, compound

Participants

Reaction Steps

A mixture containing 1 g of 4-chloro-2-methyl-6,7-dihydro-8H-pyrimido[5,4-b][1,4]oxazin-7-one (Khim. Geterotsikl. Soed. 1976, 681), 10 ml of n-butanol and 1.58 g of 1-ethoxycarbonylpiperazine is refluxed under protection against moisture and carbon dioxide, then evaporated. The residue is triturated with water and the product precipitated at 0° to 4° C. is filtered, washed with water and ether and dried to give 1.4 g (87%) of product, m.p.: 197°-198° C.

Provenance & Evidence