Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1253207Generated: October 31, 2026

Acetic Acid → 2-methyl-1H-benzimidazole-5-carboxylic acid

https://huagongshe.com/reaction/1253207

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
Reactant3,4-Diaminobenzoic acidHCID 69263—
SolventHydrochloric AcidHCID 313—
Product2-methyl-1H-benzimidazole-5-carboxylic acidHCID 1132609—

Reaction Steps

100 g (0.657 mol) of 3,4-diaminobenzoic acid are boiled under reflux with 47.3 g (0.788 mol) of glacial acetic acid and 600 ml of 4N HCl in analogy to Example 14a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04748163
Source datasetuspto-grants-1988_05
ORD IDord-27c267e0900041729f6643f68feb8e22
Source noteuspto-grants-1988_05