HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 70046943, compound → HCID 70047231, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 70046943 | HCID 70046943 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 70047231 | HCID 70047231 | — |
Reaction Steps
Flash chromatography (LPS-1 silica gel, 70:30 hexanes-ethyl acetate) of the mother liquor resulting from the trituration from ether of the crude (cis)-3-hydroxy-1,3,4,5-tetrahydro-4-(4-methoxyphenyl)-2H-1-benzazepin-2-one (see example 2E) afforded the title trans isomer, melting point 168°-170° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04748239 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-93922097a4984a2ab68ea65fbee2f2b3 |
| Source note | uspto-grants-1988_05 |