Potassium Iodide → HCID 70408646, compound

Participants

Reaction Steps

To a stirred mixture of 10 g of 3-(α-hydroxyhexyl)phenol, 7.8 g of potassium carbonate, and 4 g of potassium iodide in 400 ml of DMF was added 13.2 g of Ethyl 2-bromo-2(4-methoxyphenyl)acetate and stirring was continuted at room temperature for 40 hours. The reaction mixture was then diluted with water, extracted with ethyl acetate, dried over magnesium sulfate and evaporated to dryness. The oily residue (8 g) was chromatographed by HPLC using EtOAc-hexane (1:4) as eluent to give pure product.

Provenance & Evidence