HuagongsheHuagongshe Chemistry Print Report · For research reference only
Urea → HCID 70506031, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Urea | HCID 1176 | — |
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | Isocyanate | HCID 105034 | — |
| Reactant | HCID 70042202 | HCID 70042202 | — |
| Reactant | HCID 178418268 | HCID 178418268 | — |
| Solvent | Dichloromethane ethylacetate | HCID 21226138 | — |
| Product | HCID 70506031 | HCID 70506031 | — |
Reaction Steps
Analogously to Example 1, 295 mg of 9,10-didehydro-6-n-propyl-8α-ergoline carboxylic acid amide is reacted with lead (IV) acetate to the isocyanate, which latter compound reacts with diethylamine to the corresponding urea. After the reaction mixture has been worked up, chromatography on aluminum oxide with methylene chloride-ethyl acetate yields 120 mg of 3-(9,10-didehydro-6-n-propyl-8α-ergolinyl)-1,1-diethylurea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04748248 |
| Source dataset | uspto-grants-1988_05 |
| ORD ID | ord-1e3388912e2045039ed2dcd8c4de0961 |
| Source note | uspto-grants-1988_05 |