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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1253518Generated: November 4, 2026

5-Hydroxy-1,8-naphthyridine-2,6-dicarboxylic acid → HCID 178516463, compound

https://huagongshe.com/reaction/1253518

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Hydroxy-1,8-naphthyridine-2,6-dicarboxylic acidHCID 178524139—
SolventQuinolineHCID 7047—
ProductHCID 178516463HCID 178516463—

Reaction Steps

To quinoline (500 ml) was added 5-hydroxy-1,8-naphthyridine-2,6-dicarboxylic acid (50 g, 340 mmol). The reaction mixture was heated to reflux. After 8 hours, the reaction mixture was cooled and concentrated in vacuo to afford 1,8-naphthyridin-4-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455477B2
Source datasetuspto-grants-2013_06
ORD IDord-a4f02701fbec4e1494183cd36e7ee939
Source noteuspto-grants-2013_06